UO Second Age

Not huge one, but I do remember necro reagents being server up rares, (used to be able to get deamons blood from vesper mage shop).

http://web.archive.org/web/199812120219 ... atics.com/

under "tome of reagent"

I'm guessing changing them now though would probably tweak the economy as there's alot of these floating around since they drop.